Therapeutic Effects of Conditioned Medium of Neural Differentiated Human Bone Marrow-Derived Stem Cells on Rotenone-Induced Alpha-Synuclein Aggregation and Apoptosis
Mesenchymal stem cells (MSCs) have been used against several diseases. Their potential mainly appears from its secreted biomolecules. Human bone marrow-derived stem cells (hBMSC) displayed neuronal functional characteristics after differentiation by basic fibroblast growth factor (bFGF) and forskoli...
Main Authors: | Mahesh Ramalingam, Sujeong Jang, Han-Seong Jeong |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2021-01-01
|
Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2021/6658271 |
Similar Items
-
Neural-Induced Human Adipose Tissue-Derived Stem Cells Conditioned Medium Ameliorates Rotenone-Induced Toxicity in SH-SY5Y Cells
by: Mahesh Ramalingam, et al.
Published: (2021-02-01) -
Biophysical Characterization of α-Synuclein and Rotenone Interaction
by: Anthony L. Fink, et al.
Published: (2013-09-01) -
SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine
by: Lin-nan Zhu, et al.
Published: (2018-08-01) -
The Impairments of α-Synuclein and Mechanistic Target of Rapamycin in Rotenone-Induced SH-SY5Y Cells and Mice Model of Parkinson’s Disease
by: Mahesh Ramalingam, et al.
Published: (2019-09-01) -
Protein aggregation containing beta-amyloid, alpha-synuclein and hyperphosphorylated tau in cultured cells of hippocampus, substantia nigra and locus coeruleus after rotenone exposure
by: Martins Stephanie A, et al.
Published: (2010-11-01)