Neonatal LPS Administered Before Sensitization Reduced the Number of Inflammatory Monocytes and Abrogated the Development of OVA-Induced Th2 Allergic Airway Inflammation

Neonatal LPS Administered Before Sensitization Reduced the Number of Inflammatory Monocytes and Abrogated the Development of OVA-Induced Th2 Allergic Airway Inflammation

It is becoming increasingly clear that environment factors during early life play a pivotal role in the development of allergic asthma. Among these, a traditional farm is one of the strongest protective environments, and the protective effects have been, at least in part, attributed to the high-leve...

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Bibliographic Details
Main Authors: Liuchuang Gao, Min Wu, Hangyu Liu, Miao He, Han Jiang, Runshi Shang, Qiangqiang Wang, Zhu Song, Yafei Huang, Junyan Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
neonates
time window
LPS
hygiene hypothesis
allergic asthma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.725906/full

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