MATHEMATICAL MODEL OF DIAGNOSTICS OF PERINATAL DAMAGE OF THE CENTRAL NERVOUS SYSTEM IN INFANTS IN THE NEONATAL PERIOD

• Main Authors: I. V. Shalkevich, A. N. Tyrsin, D. V. Ostroushko, O. V. Shalkevich
• Format: Article
• Language: Russian
• Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2017-06-01
• Series: Rossijskij Vestnik Perinatologii i Pediatrii
• Subjects: perinatal damage of the central nervous system; ultrasonic examination of brain; doppler study of cerebral vessels; prognostic rule; disability prevention
• Online Access: https://www.ped-perinatology.ru/jour/article/view/504

Questions of relevance and timeliness of diagnostics of perinatal disturbances of the central nervous system in newborns are considered in the article. Research objective was to determine the reliable recognition of the development of newborn encephalopathy at the age of the first two weeks of life according to neurological examination and neurosonography parameters with Doppler study of cerebral vessels. Features of the neurology status and data of ultrasonic examination of brain with Doppler study of cerebral vessels in 58 newborns with pathology of the nervous system and 23 healthy newborns are investigated. 10 sings of the neurological status and 10 parameters of ultrasonic examination are analyzed. By results of the obtained findings, prognostic rule is developed, governed by application of discriminant analysis of the studied signs, allowing to diagnose encephalopathy in newborn with sensitivity and specificity of 95% in the first week of life. Its application promotes timely identification and the beginning of therapy at infants from risk group of development of severe neurological dysfunction and preventing the growth of disability among infants.