Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians

Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians

Abstract Background Human aging is a hot topic in biology, and it has been associated with DNA methylation changes at specific genomic sites. We aimed to study the changes of DNA methylation at a single-CpG-site resolution using peripheral blood samples from centenarians. Methods Using Illumina 450 ...

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Bibliographic Details
Main Authors: Qian Zeng, Xiaoping Chen, Chaoxue Ning, Qiao Zhu, Yao Yao, Yali Zhao, Fuxin Luan
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Medical Genomics
Subjects:
DNA methylation
Aging
ROD1
NLRC5
HKR1
Online Access:http://link.springer.com/article/10.1186/s12920-018-0334-1

Internet

http://link.springer.com/article/10.1186/s12920-018-0334-1

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