Sesamin suppresses LPS-induced microglial activation via regulation of TLR4 expression

Sesamin, one of the most abundant lignans in sesame seeds and oils, is well known for neuroprotective activity. However, its effects on toll-like-receptor 4 (TLR4), the key innate immune receptor implicated in microglia activation and neuroinflammation has not been reported. Our study demonstrated t...

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Bibliographic Details
Main Authors: Sasimol Udomruk, Chayanut Kaewmool, Peraphan Pothacharoen, Thanyaluck Phitak, Prachya Kongtawelert
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618304407