High mobility group box 1 protein (HMGB1) stimulates the nuclear accumulation of p53

High mobility group box 1 protein (HMGB1) stimulates the nuclear accumulation of p53

p53 is usually regarded as a tumour suppressor protein but its constant activation may result in pro-tumorigenic inflammation. The activation of p53 can be provoked by an increase in its concentration as a result of high level transcription, by transformation of the p53 protein to an active conforma...

Full description

Bibliographic Details
Main Authors: Maria Schröder, Shazie Yusein-Myashkova, Jordana Todorova, Evdokia Pasheva, Iva Ugrinova
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
hmgb1
c terminus
p53
nuclear localisation
Online Access:http://dx.doi.org/10.1080/13102818.2019.1604159

Similar Items

Similar Items