Multifunctional Roles of the Actin-Binding Protein Flightless I in Inflammation, Cancer and Wound Healing

Multifunctional Roles of the Actin-Binding Protein Flightless I in Inflammation, Cancer and Wound Healing

Flightless I is an actin-binding member of the gelsolin family of actin-remodeling proteins that inhibits actin polymerization but does not possess actin severing ability. Flightless I functions as a regulator of many cellular processes including proliferation, differentiation, apoptosis, and migrat...

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Bibliographic Details
Main Authors: Xanthe L. Strudwick, Allison J. Cowin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Flightless I
actin-binding protein
wound healing
inflammation
cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.603508/full

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