APPLICATIONS OF PHARMACOGENETIC TESTING FOR PERSONALIZATION OF THERAPY WITH ORAL ANTICOAGULANTS IN RUSSIA

APPLICATIONS OF PHARMACOGENETIC TESTING FOR PERSONALIZATION OF THERAPY WITH ORAL ANTICOAGULANTS IN RUSSIA

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The clinical significance of the patient genetic characteristics in the individual pharmacological response to oral anticoagulants is considered. Possible tactics of warfarin dosing and new oral anticoagulants choice on the basis of pharmacogenetic testing as well as indications for this approach in...

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Bibliographic Details
Main Authors: D. A. Sychev, R. E. Kazakov, V. A. Otdelenov, A. B. Prokofiev
Format: Article
Language:English
Published: Stolichnaya Izdatelskaya Kompaniya 2015-09-01
Series:Racionalʹnaâ Farmakoterapiâ v Kardiologii
Subjects:
anticoagulants
warfarin
new oral anticoagulants
dabigatran
pharmacogenetics
cyp2c9
vkorc1
ces1
Online Access:https://www.rpcardio.com/jour/article/view/220
Description
Summary:The clinical significance of the patient genetic characteristics in the individual pharmacological response to oral anticoagulants is considered. Possible tactics of warfarin dosing and new oral anticoagulants choice on the basis of pharmacogenetic testing as well as indications for this approach in clinical practice are discussed. It should increase efficacy and safety of anticoagulant therapy.
ISSN:1819-6446
2225-3653

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