Fast Intracortical Sensory-Motor Integration: A Window Into the Pathophysiology of Parkinson’s Disease

Fast Intracortical Sensory-Motor Integration: A Window Into the Pathophysiology of Parkinson’s Disease

Parkinson’s Disease (PD) is a prototypical basal ganglia disorder. Nigrostriatal dopaminergic denervation leads to progressive dysfunction of the cortico-basal ganglia-thalamo-cortical sensorimotor loops, causing the classical motor symptoms. Although the basal ganglia do not receive direct sensory...

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Bibliographic Details
Main Authors: Raffaele Dubbioso, Fiore Manganelli, Hartwig Roman Siebner, Vincenzo Di Lazzaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Human Neuroscience
Subjects:
short-latency afferent inhibition
cholinergic neuromodulation
cortical oscillations
dopaminergic dysfunction
Parkinson’s disease
movement disorder
Online Access:https://www.frontiersin.org/article/10.3389/fnhum.2019.00111/full

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