A Computational Approach for the Prediction of Treatment History and the Effectiveness or Failure of Antiretroviral Therapy

A Computational Approach for the Prediction of Treatment History and the Effectiveness or Failure of Antiretroviral Therapy

Human Immunodeficiency Virus Type 1 (HIV-1) infection is associated with high mortality if no therapy is provided. Currently, the treatment of an HIV-1 positive patient requires that several drugs should be taken simultaneously. The resistance of the virus to an antiretroviral drug may lead to treat...

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Bibliographic Details
Main Authors: Olga Tarasova, Nadezhda Biziukova, Dmitry Kireev, Alexey Lagunin, Sergey Ivanov, Dmitry Filimonov, Vladimir Poroikov
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
human immunodeficiency virus type 1
hiv-1
treatment history
therapy failure
protease
reverse transcriptase
pass
random forest
Online Access:https://www.mdpi.com/1422-0067/21/3/748

Internet

https://www.mdpi.com/1422-0067/21/3/748

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