Neutrophil Evolution and Their Diseases in Humans
Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration...
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Frontiers Media S.A.
2017-08-01
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| Series: | Frontiers in Immunology |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.01009/full |
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doaj-20f7af273d914cde8c29d059579919f92020-11-24T21:56:01ZengFrontiers Media S.A.Frontiers in Immunology1664-32242017-08-01810.3389/fimmu.2017.01009277587Neutrophil Evolution and Their Diseases in HumansJennifer W. Leiding0Jennifer W. Leiding1Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, Tampa, FL, United StatesJohns Hopkins All Children’s Hospital, St. Petersburg, FL, United StatesGranulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration, chemotaxis, and function cause a spectrum of primary immune defects characterized by host susceptibility to invasive infections.http://journal.frontiersin.org/article/10.3389/fimmu.2017.01009/fullneutrophilneutropeniachemotaxisimmunodeficiencygranulocytes |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Jennifer W. Leiding Jennifer W. Leiding |
| spellingShingle |
Jennifer W. Leiding Jennifer W. Leiding Neutrophil Evolution and Their Diseases in Humans Frontiers in Immunology neutrophil neutropenia chemotaxis immunodeficiency granulocytes |
| author_facet |
Jennifer W. Leiding Jennifer W. Leiding |
| author_sort |
Jennifer W. Leiding |
| title |
Neutrophil Evolution and Their Diseases in Humans |
| title_short |
Neutrophil Evolution and Their Diseases in Humans |
| title_full |
Neutrophil Evolution and Their Diseases in Humans |
| title_fullStr |
Neutrophil Evolution and Their Diseases in Humans |
| title_full_unstemmed |
Neutrophil Evolution and Their Diseases in Humans |
| title_sort |
neutrophil evolution and their diseases in humans |
| publisher |
Frontiers Media S.A. |
| series |
Frontiers in Immunology |
| issn |
1664-3224 |
| publishDate |
2017-08-01 |
| description |
Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration, chemotaxis, and function cause a spectrum of primary immune defects characterized by host susceptibility to invasive infections. |
| topic |
neutrophil neutropenia chemotaxis immunodeficiency granulocytes |
| url |
http://journal.frontiersin.org/article/10.3389/fimmu.2017.01009/full |
| work_keys_str_mv |
AT jenniferwleiding neutrophilevolutionandtheirdiseasesinhumans AT jenniferwleiding neutrophilevolutionandtheirdiseasesinhumans |
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1725859973152374784 |