Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity
Summary: The ability to generate large numbers of distinct types of human dendritic cells (DCs) in vitro is critical for accelerating our understanding of DC biology and harnessing them clinically. We developed a DC differentiation method from human CD34+ precursors leading to high yields of plasmac...
Main Authors: | Sreekumar Balan, Catharina Arnold-Schrauf, Abdenour Abbas, Norbert Couespel, Juliette Savoret, Francesco Imperatore, Alexandra-Chloé Villani, Thien-Phong Vu Manh, Nina Bhardwaj, Marc Dalod |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718311239 |
Similar Items
-
Measurement of Opening Displacement of Single and Bifurcated Notches by Moiré Interferometry
by: Kimura H., et al.
Published: (2010-06-01) -
Harnessing mechanistic knowledge on beneficial versus deleterious IFN-I effects to design innovative immunotherapies targeting cytokine activity to specific cell types
by: Marc eDALOD, et al.
Published: (2014-10-01) -
S-phase favours notch cell responsiveness in the Drosophila bristle lineage.
by: Sylvie Remaud, et al.
Published: (2008-01-01) -
Mastering self-renewal for lineage reprogramming : Application to macrophage to beta cell conversion
by: Imperatore, Francesco
Published: (2013) -
Investigating evolutionary conservation of dendritic cell subset identity and functions
by: Thien-Phong eVu Manh, et al.
Published: (2015-06-01)