The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion

The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion

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Prosaposin (PSAP), a highly conserved glycoprotein, is a precursor of saposins A–D. Accumulating evidence suggests that PSAP is a neurotrophic factor, as well as a regulator of lysosomal enzymes. Recently, the orphan G-protein-coupled receptors GPR37 and GPR37L1 were recognized as PSAP receptors, bu...

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Bibliographic Details
Main Authors: Miho Taniguchi, Hiroaki Nabeka, Kimiko Yamamiya, Md. Sakirul Islam Khan, Tetsuya Shimokawa, Farzana Islam, Takuya Doihara, Hiroyuki Wakisaka, Naoto Kobayashi, Fumihiko Hamada, Seiji Matsuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357083/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357083/?tool=EBI

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