Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering
Even though hematogenous spread of the Lyme disease spirochete, Borrelia burgdorferi, has been well documented, and there are more than 300,000 cases per year of Lyme disease in the United States, no evidence (anecdotal or published) of transfusion-associated Lyme disease has been reported. Such a p...
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Frontiers Media S.A.
2018-09-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fmicb.2018.02070/full |
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doaj-20ee94285319413d949bb1f807618e7b2020-11-24T21:21:31ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2018-09-01910.3389/fmicb.2018.02070409118Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth ConsideringCharles S. Pavia0Maria M. Plummer1Department of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine, New York, NY, United StatesDepartment of Clinical Specialties, New York Institute of Technology College of Osteopathic Medicine, New York, NY, United StatesEven though hematogenous spread of the Lyme disease spirochete, Borrelia burgdorferi, has been well documented, and there are more than 300,000 cases per year of Lyme disease in the United States, no evidence (anecdotal or published) of transfusion-associated Lyme disease has been reported. Such a possibility would seem to exist but various factors, as discussed in this perspective, make this less likely to occur. Nonetheless, if not done already, safeguards need to be put in place at blood collection and dispensing facilities, possibly with the assistance of diagnostic microbiology and immunology laboratories, to ensure that the potential for the transfer of the Lyme disease spirochete through a blood transfusion remains a theoretical consideration rather than a real possibility.https://www.frontiersin.org/article/10.3389/fmicb.2018.02070/fulllyme diseaseBorrelia burgdorferihematogenous spreadblood donorblood transfusiondiagnostic testing |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Charles S. Pavia Maria M. Plummer |
| spellingShingle |
Charles S. Pavia Maria M. Plummer Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering Frontiers in Microbiology lyme disease Borrelia burgdorferi hematogenous spread blood donor blood transfusion diagnostic testing |
| author_facet |
Charles S. Pavia Maria M. Plummer |
| author_sort |
Charles S. Pavia |
| title |
Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering |
| title_short |
Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering |
| title_full |
Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering |
| title_fullStr |
Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering |
| title_full_unstemmed |
Transfusion-Associated Lyme Disease – Although Unlikely, It Is Still a Concern Worth Considering |
| title_sort |
transfusion-associated lyme disease – although unlikely, it is still a concern worth considering |
| publisher |
Frontiers Media S.A. |
| series |
Frontiers in Microbiology |
| issn |
1664-302X |
| publishDate |
2018-09-01 |
| description |
Even though hematogenous spread of the Lyme disease spirochete, Borrelia burgdorferi, has been well documented, and there are more than 300,000 cases per year of Lyme disease in the United States, no evidence (anecdotal or published) of transfusion-associated Lyme disease has been reported. Such a possibility would seem to exist but various factors, as discussed in this perspective, make this less likely to occur. Nonetheless, if not done already, safeguards need to be put in place at blood collection and dispensing facilities, possibly with the assistance of diagnostic microbiology and immunology laboratories, to ensure that the potential for the transfer of the Lyme disease spirochete through a blood transfusion remains a theoretical consideration rather than a real possibility. |
| topic |
lyme disease Borrelia burgdorferi hematogenous spread blood donor blood transfusion diagnostic testing |
| url |
https://www.frontiersin.org/article/10.3389/fmicb.2018.02070/full |
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