The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line

The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line

The effects of tanshinone IIA on the proliferation of the human non-small cell lung cancer cell line A549 and its possible mechanism on the VEGF/VEGFR signal pathway were investigated. The exploration of the interaction between tanshinone IIA and its target proteins provides a feasible platform for...

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Bibliographic Details
Main Authors: Jun Xie, Jiahui Liu, Heng Liu, Shihui Liang, Meigui Lin, Yueyu Gu, Taoli Liu, Dongmei Wang, Hui Ge, Sui-lin Mo
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Non-small cell lung cancer
Tanshinone IIA
VEGF/VEGFR signal pathway
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383515001161

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