Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking

Cerebellar Purkinje cells (PCs) linearly encode whisker position but the precise circuit mechanisms that generate these signals are not well understood. Here the authors use patch clamp recordings to show that selective tuning of granule cell inputs and bidirectional tuning of interneuron inputs are...

Full description

Bibliographic Details
Main Authors:	Susu Chen, George J. Augustine, Paul Chadderton
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-017-00312-1

id	doaj-20e260e620ab437db7eed40df84a17ee
record_format	Article
spelling	doaj-20e260e620ab437db7eed40df84a17ee2021-01-31T12:28:07ZengNature Publishing GroupNature Communications2041-17232017-08-018111310.1038/s41467-017-00312-1Serial processing of kinematic signals by cerebellar circuitry during voluntary whiskingSusu Chen0George J. Augustine1Paul Chadderton2Department of Bioengineering and Centre for Neurotechnology, Imperial College LondonLee Kong Chian School of Medicine, Nanyang Technological UniversityDepartment of Bioengineering and Centre for Neurotechnology, Imperial College LondonCerebellar Purkinje cells (PCs) linearly encode whisker position but the precise circuit mechanisms that generate these signals are not well understood. Here the authors use patch clamp recordings to show that selective tuning of granule cell inputs and bidirectional tuning of interneuron inputs are required to generate the kinematic representations in PCs.https://doi.org/10.1038/s41467-017-00312-1
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Susu Chen George J. Augustine Paul Chadderton
spellingShingle	Susu Chen George J. Augustine Paul Chadderton Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking Nature Communications
author_facet	Susu Chen George J. Augustine Paul Chadderton
author_sort	Susu Chen
title	Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
title_short	Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
title_full	Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
title_fullStr	Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
title_full_unstemmed	Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
title_sort	serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-08-01
description	Cerebellar Purkinje cells (PCs) linearly encode whisker position but the precise circuit mechanisms that generate these signals are not well understood. Here the authors use patch clamp recordings to show that selective tuning of granule cell inputs and bidirectional tuning of interneuron inputs are required to generate the kinematic representations in PCs.
url	https://doi.org/10.1038/s41467-017-00312-1
work_keys_str_mv	AT susuchen serialprocessingofkinematicsignalsbycerebellarcircuitryduringvoluntarywhisking AT georgejaugustine serialprocessingofkinematicsignalsbycerebellarcircuitryduringvoluntarywhisking AT paulchadderton serialprocessingofkinematicsignalsbycerebellarcircuitryduringvoluntarywhisking
_version_	1724317182680104960

Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking

Similar Items