Hydrogen sulfide prodrugs—a review

Hydrogen sulfide (H2S) is recognized as one of three gasotransmitters together with nitric oxide (NO) and carbon monoxide (CO). As a signaling molecule, H2S plays an important role in physiology and shows great potential in pharmaceutical applications. Along this line, there is a need for the develo...

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Main Authors:	Yueqin Zheng, Xingyue Ji, Kaili Ji, Binghe Wang
Format:	Article
Language:	English
Published:	Elsevier 2015-09-01
Series:	Acta Pharmaceutica Sinica B
Subjects:	Hydrogen sulfide (H2S) Gasotransmitters H2S prodrugs H2S-hybrid nonsteroidal anti-inflammatory drugs Controllable H2S prodrugs Hydrolysis-based H2S prodrugs
Online Access:	http://www.sciencedirect.com/science/article/pii/S221138351500091X

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spelling	doaj-20da590b237149869cc890b7ebf0b3652020-11-24T23:52:57ZengElsevierActa Pharmaceutica Sinica B2211-38352211-38432015-09-015536737710.1016/j.apsb.2015.06.004Hydrogen sulfide prodrugs—a reviewYueqin ZhengXingyue JiKaili JiBinghe WangHydrogen sulfide (H2S) is recognized as one of three gasotransmitters together with nitric oxide (NO) and carbon monoxide (CO). As a signaling molecule, H2S plays an important role in physiology and shows great potential in pharmaceutical applications. Along this line, there is a need for the development of H2S prodrugs for various reasons. In this review, we summarize different H2S prodrugs, their chemical properties, and some of their potential therapeutic applications.http://www.sciencedirect.com/science/article/pii/S221138351500091XHydrogen sulfide (H2S)GasotransmittersH2S prodrugsH2S-hybrid nonsteroidal anti-inflammatory drugsControllable H2S prodrugsHydrolysis-based H2S prodrugs
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yueqin Zheng Xingyue Ji Kaili Ji Binghe Wang
spellingShingle	Yueqin Zheng Xingyue Ji Kaili Ji Binghe Wang Hydrogen sulfide prodrugs—a review Acta Pharmaceutica Sinica B Hydrogen sulfide (H2S) Gasotransmitters H2S prodrugs H2S-hybrid nonsteroidal anti-inflammatory drugs Controllable H2S prodrugs Hydrolysis-based H2S prodrugs
author_facet	Yueqin Zheng Xingyue Ji Kaili Ji Binghe Wang
author_sort	Yueqin Zheng
title	Hydrogen sulfide prodrugs—a review
title_short	Hydrogen sulfide prodrugs—a review
title_full	Hydrogen sulfide prodrugs—a review
title_fullStr	Hydrogen sulfide prodrugs—a review
title_full_unstemmed	Hydrogen sulfide prodrugs—a review
title_sort	hydrogen sulfide prodrugs—a review
publisher	Elsevier
series	Acta Pharmaceutica Sinica B
issn	2211-3835 2211-3843
publishDate	2015-09-01
description	Hydrogen sulfide (H2S) is recognized as one of three gasotransmitters together with nitric oxide (NO) and carbon monoxide (CO). As a signaling molecule, H2S plays an important role in physiology and shows great potential in pharmaceutical applications. Along this line, there is a need for the development of H2S prodrugs for various reasons. In this review, we summarize different H2S prodrugs, their chemical properties, and some of their potential therapeutic applications.
topic	Hydrogen sulfide (H2S) Gasotransmitters H2S prodrugs H2S-hybrid nonsteroidal anti-inflammatory drugs Controllable H2S prodrugs Hydrolysis-based H2S prodrugs
url	http://www.sciencedirect.com/science/article/pii/S221138351500091X
work_keys_str_mv	AT yueqinzheng hydrogensulfideprodrugsareview AT xingyueji hydrogensulfideprodrugsareview AT kailiji hydrogensulfideprodrugsareview AT binghewang hydrogensulfideprodrugsareview
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Hydrogen sulfide prodrugs—a review

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