Accuracy assessment of combined diffusion weighed and dynamic gadolinium MR sequences in characterization of salivary gland tumors

• Main Authors: Lamya Eissa, Shadia Abou Seif, Salah El Desooky, Mohamed Eid, Tarek Koraitim
• Format: Article
• Language: English
• Published: SpringerOpen 2016-03-01
• Series: The Egyptian Journal of Radiology and Nuclear Medicine
• Subjects: Diffusion; Dynamic MRI; Parotid neoplasms
• Online Access: http://www.sciencedirect.com/science/article/pii/S0378603X15002557

Background: The salivary glandular tumors are challenging as regards preoperative diagnosis and MRI with the use of DWI and DCE are evaluated in accuracy for characterization of salivary masses. Methods: The study included 53 patients who underwent MRI-DWI and DCE and diagnosis was made by diagnostic scheme of ADC-values and four types of DCE curves. Results: Pleomorphic adenomas had the highest of all ADC values on DWI (⩾1.4 × 10−3 cm2/s), and Warthin tumors had low values (0.6–0.8 × 10−3 cm2/s), while malignant tumors had intermediate values (0.8–1.2 × 10−3 cm2/s). Type A curve predominated the pleomorphic adenomas, type B curve predominated Warthin, and other lymphoid lesions as lymphoma. Type C curve predominated malignant lesions. Statistical analysis showed combination intermediate ADC (in range of 0.8 to <1.4 × 10−3 cm2/s) and type C as useful test of malignancy with high accuracy of 90.5%. Conclusion: DWI and dynamic enhancement curves with combined interpretation of both techniques and in view of the concluded values can provide valuable data in characterization of salivary glandular tumors.