Antioxidant Activities of Alkyl Substituted Pyrazine Derivatives of Chalcones—In Vitro and In Silico Study

Antioxidant Activities of Alkyl Substituted Pyrazine Derivatives of Chalcones—In Vitro and In Silico Study

Chalcones are polyphenolic secondary metabolites of plants, many of which have antioxidant activity. Herein, a set of 26 synthetic chalcone derivatives with alkyl substituted pyrazine heterocycle A and four types of the monophenolic ring B, were evaluated for the potential radical scavenging and ant...

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Bibliographic Details
Main Authors: Višnja Stepanić, Mario Matijašić, Tea Horvat, Donatella Verbanac, Marta Kučerová-Chlupáčová, Luciano Saso, Neven Žarković
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Antioxidants
Subjects:
antioxidant
chalcone-like
DFT
in silico
in vitro
pyrazine
radical scavenging
Online Access:https://www.mdpi.com/2076-3921/8/4/90

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