| Summary: | <i>Purpose</i>: The purpose of this study was to investigate the findings of electrodiagnostic studies (nerve conduction study (NCS) and electromyography (EMG)) in patients with moderate and severe lumbar central spinal stenosis (LCSS). <i>Methods</i>: We retrospectively reviewed the medical records of Ulsan University Hospital and identified 32 consecutive patients (mean age = 66.9 ± 7.4 years; male:female = 8:24) with LCSS. Based on the results of T2 axial magnetic resonance imaging at the level of L4–5, patients were categorized as having severe (<i>n</i> = 14) or moderate LCSS (<i>n</i> = 18). Results from NCS and EMG were retrieved. Additionally, we included 15 age- and sex-matched volunteers without LCSS (mean age = 65.2 ± 8.0 years; male:female = 4:11) to serve as a control group. Results of NCS and EMG were compared between the three groups. <i>Results</i>: We found that, compared to normal subjects, patients with moderate or severe LCSS presented significantly lower distal amplitudes of the compound motor action potential of both peroneal and tibial nerves. Regarding EMG, positive sharp waves and fibrillation potentials were exclusively observed in patients with severe LCSS group (28.6%). <i>Conclusion</i>: Electrodiagnostic studies were significantly altered in patients with moderate and severe LCSS. Our results may be helpful to diagnose LCSS-induced radiculopathy and to differentiate it from other causes of peripheral nerve pathologies.
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