Applying the D50 disease progression model to gray and white matter pathology in amyotrophic lateral sclerosis
Therapeutic management and research in Amyotrophic Laterals Sclerosis (ALS) have been limited by the substantial heterogeneity in progression and anatomical spread that are endemic of the disease. Neuroimaging biomarkers represent powerful additions to the current monitoring repertoire but have yiel...
Main Authors: | Robert Steinbach, Meerim Batyrbekova, Nayana Gaur, Annika Voss, Beatrice Stubendorff, Thomas E. Mayer, Christian Gaser, Otto W. Witte, Tino Prell, Julian Grosskreutz |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | NeuroImage: Clinical |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158219304413 |
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