"Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA).

"Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA).

CaV2.2 (N-type) voltage-gated calcium channels (Ca2+ channels) play key roles in neurons and neuroendocrine cells including the control of cellular excitability, neurotransmitter / hormone secretion, and gene expression. Calcium entry is precisely controlled by channel gating properties including mu...

Full description

Bibliographic Details
Main Authors:	Lei Zhu, Sarah McDavid, Kevin P M Currie
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4519294?pdf=render

Similar Items

Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain
by: Mark Dzietko, et al.
Published: (2015-01-01)

Induction of 12-lipoxygenase expression by phorbol 12-myristate 13-acetate (PMA) in human epidermoid carcinoma A431 cells
by: Liaw, Yu-Wei, et al.
Published: (1997)

Inhibition of the expression of phospholipid hydroperoxide glutathione peroxidase by Phorbol 12-Myristate 13-Acetate (PMA) and sodium arsenite in endothelial cells
by: Ing-Kai Lin, et al.
Published: (1999)

A Label-Free Quantitative Proteomic Analysis of Mouse Neutrophil Extracellular Trap Formation Induced by Streptococcus suis or Phorbol Myristate Acetate (PMA)
by: Xiaoping Wang, et al.
Published: (2018-11-01)

NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages.
by: Min-Gu Song, et al.
Published: (2015-01-01)

REGULATION OF TLR/RLR GENE ACTIVITY AND SYNTHESIS OF CYTOKINES DURING PHORBOL MYRISTATE ACETATE (PMA)-INDUCED DIFFERENTIATION OF THP-1 MONOCYTES INTO MACROPHAGE-LIKE CELLS
by: T. M. Sokolova, et al.
Published: (2017-01-01)

Biopacemaker acceleration without increased synchronization by chronic exposure to phorbol myristate acetate
by: Alami Alamdari, Yashar
Published: (2016)

Phorbol 12-Myristate 13-Acetate Induces MUC16 Expression via PKCδ and p38 in Human Airway Epithelial Cells
by: Chang Hoon Bae, et al.
Published: (2012-09-01)

A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture
by: Divya Padma, et al.
Published: (2016-01-01)

Early events associated with phorbol myristate acetate-stimulated HL-60 cells differentiation
by: Wang, Ying Kai, et al.
Published: (1996)

Early Events Associated with Phorbol Myristate Acetate- Stimulated HL-60 Cells Differentiation
by: Wang, Ing-Kae, et al.
Published: (1996)

Nanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment
by: Zhou ZL, et al.
Published: (2016-12-01)

Effects of phorbol myristate acetate and sivelestat on the lung injury caused by fat embolism in isolated lungs
by: Lin Chia-Chih, et al.
Published: (2012-01-01)

Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs
by: Lin Chia-Chih, et al.
Published: (2012-03-01)

Functional characterization of equine neutrophils in response to calcium ionophore A23187 and phorbol myristate acetate
by: Moore, Tabitha Gale Bryant
Published: (2014)

Antioxidant and Antiradical Activities of Manihot esculenta Crantz (Euphorbiaceae) Leaves and Other Selected Tropical Green Vegetables Investigated on Lipoperoxidation and Phorbol-12-myristate-13-acetate (PMA) Activated Monocytes
by: Ange Mouithys-Mickalad, et al.
Published: (2011-09-01)

Effect of dietary flavonoids on phorbol 12-myristate 13-acetate-induced cyclooxygenase-2 expression in human breast cells.
Published: (2007)

The phorbol 12-myristate-13-acetate differentiation protocol is critical to the interaction of THP-1 macrophages with Salmonella Typhimurium.
by: Tregei Starr, et al.
Published: (2018-01-01)

Effects of Phorbol Myristate Acetate and Dibuty1 Cyclic AMP on Muscarinic Receptor-coupled Signals and Cell Proliferation
by: 張琪媛
Published: (1994)

Induction of p21 WAF1/CIP1 of expression by Phorbol 12-Myristate 13-Actate (PMA) in human epidermoid carcinoma A431 cells
by: Mei-Chen Liao, et al.
Published: (2001)

Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells
by: Huang Y, et al.
Published: (2018-09-01)

Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression
by: Chuu-Yun A. Wong, et al.
Published: (2016-03-01)

Effect of sphingosine and phorbol-12-myristate-13-acetate on the growth and dimethylsulfoxide-induced differentiation in the insect trypanosomatid Herpetomonas samuelpessoai
by: André Luis Souza dos Santos, et al.
Published: (2007-08-01)

Sustained small and intermediate size proteins expression in phorbol 12-myristate 13-acetate/ionomycine prolonged stimulated human fibroblasts
by: Zeinab Abedian, et al.
Published: (2017-05-01)

"The adherence and functional properties of mice peritoneal macrophage phagocytic system with Phorbol Myristate Acetate stimulation and Nitroblue Tetrazolium reduction assay "
by: Mosaffa N, et al.
Published: (2002-11-01)

Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway
by: Justin B. Davis, et al.
Published: (2018-05-01)

The involvement of LPA/RhoA/ROCK signaling pathway inPhorbol-12-Myristate-13-Acetate-induced survival and death
by: Lai, Jin-Mei, et al.
Published: (2002)

Effects of phorbol 12-myristate 13-acetate on triglyceride and cholesteryl ester synthesis in cultured coronary smooth muscle cells and macrophages.
by: M Moinat, et al.
Published: (1990-02-01)

Bioinformatics of Differentially Expressed Genes in Phorbol 12‐Myristate 13‐Acetate‐Induced Megakaryocytic Differentiation of K562 Cells by Microarray Analysis
by: Kim, J.-E, et al.
Published: (2022)

Bioinformatics of Differentially Expressed Genes in Phorbol 12‐Myristate 13‐Acetate‐Induced Megakaryocytic Differentiation of K562 Cells by Microarray Analysis
by: Kim, J.-E, et al.
Published: (2022)

Synthesis of a Cleaved Form of Osteopontin by THP-1 Cells and Its Alteration by Phorbol 12-Myristate 13-Acetate and BCG Infection
by: Gaowa Bai, et al.
Published: (2018-01-01)

Evaluation of effects of various drugs on platelet functions using phorbol 12-myristate 13-acetate-induced megakaryocytic human erythroid leukemia cells
by: Tada T, et al.
Published: (2016-09-01)

The role of EF-hand in calmodulin binding of voltage-gated Cav2.1 and Cav2.2 calcium channels
by: Soh, Daniel Hyeongjin
Published: (2018)

Calmodulin modulates the Ca2+-dependent inactivation and expression level of bovine CaV2.2 expressed in HEK293T cells
by: Chih-Hung Chi, et al.
Published: (2017-06-01)

Effect of Dark Chocolate Extracts on Phorbol 12-Myristate 13-Acetate-Induced Oxidative Burst in Leukocytes Isolated by Normo-Weight and Overweight/Obese Subjects
by: Francesca Ioannone, et al.
Published: (2017-06-01)

Phorbol myristate acetate and Bryostatin 1 rescue IFN-gamma inducibility of MHC class II molecules in LS1034 colorectal carcinoma cell line
by: Wiseman Charles L, et al.
Published: (2003-03-01)

Evaluation of effects of various drugs on platelet functions using phorbol 12-myristate 13-acetate-induced megakaryocytic human erythroid leukemia cells [Corrigendum]
by: Tada T, et al.
Published: (2017-02-01)

Comparative Proteomic Analysis Reveals Varying Impact on Immune Responses in Phorbol 12-Myristate-13-Acetate-Mediated THP-1 Monocyte-to-Macrophage Differentiation
by: Sneha M. Pinto, et al.
Published: (2021-06-01)

The Role of p44/42 MAPK and NF-κB on Phorbol-12-Myristate-13-Acetate-Induced Cyclooxygenase-2 Expression in Human Pulmonary Epithelial Cells (A549)
by: Ming-Shyan Chang, et al.
Published: (2000)

Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo
by: Sukkum Ngullie Chang, et al.
Published: (2020-12-01)

Cannot write session to /tmp/vufind_sessions/sess_9co6e7l5i458gguoo5a4at8lpu