Identification of Disease-Related 2-Oxoglutarate/Fe (II)-Dependent Oxygenase Based on Reduced Amino Acid Cluster Strategy
The 2-oxoglutarate/Fe (II)-dependent (2OG) oxygenase superfamily is mainly responsible for protein modification, nucleic acid repair and/or modification, and fatty acid metabolism and plays important roles in cancer, cardiovascular disease, and other diseases. They are likely to become new targets f...
Main Authors: | Jian Zhou, Suling Bo, Hao Wang, Lei Zheng, Pengfei Liang, Yongchun Zuo |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-07-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.707938/full |
Similar Items
-
Industrial Application of 2-Oxoglutarate-Dependent Oxygenases
by: Christin Peters, et al.
Published: (2019-02-01) -
Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution
by: Katharina E. Bräuer, et al.
Published: (2018-06-01) -
Functional diversity of 2-oxoglutarate/Fe(II)-dependent dioxygenases in plant metabolism
by: Scott Cameron Farrow, et al.
Published: (2014-10-01) -
Genome-wide characterization of 2-oxoglutarate and Fe(II)-dependent dioxygenase family genes in tomato during growth cycle and their roles in metabolism
by: Shuo Wei, et al.
Published: (2021-02-01) -
Ascorbate as a cofactor for Fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumour growth and progression
by: Caroline eKuiper, et al.
Published: (2014-12-01)