The role of platelets and megakaryocytes in bone metastasis

Blood platelets have been known for more than a century as important partners for successful metastatic dissemination of solid tumors. Cancer cell-induced platelet activation is a key event responsible for prometastatic activity of platelets. Blocking platelet aggregation inhibits the progression of...

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Bibliographic Details
Main Authors: Raphael Leblanc, Olivier Peyruchaud
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137415300853