Local Injection of Submicron Particle Docetaxel is Associated with Tumor Eradication, Reduced Systemic Toxicity and an Immunologic Response in Uro-Oncologic Xenografts

Local Injection of Submicron Particle Docetaxel is Associated with Tumor Eradication, Reduced Systemic Toxicity and an Immunologic Response in Uro-Oncologic Xenografts

Intratumoral (IT) administration of submicron particle docetaxel (NanoDoce<sup>&#174;</sup>, NanOlogy LLC, Fort Worth, TX, USA) and its efficacy against genitourinary-oncologic xenografts in rats and mice, xenograft-site docetaxel concentrations and immune-cell infiltration were stud...

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Bibliographic Details
Main Authors: Holly A. Maulhardt, Lauren Hylle, Michael V. Frost, Ashley Tornio, Sara Dafoe, Leanne Drummond, David I. Quinn, Ashish M. Kamat, Gere S. diZerega
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
docetaxel
NanoDoce<sup>®</sup>
intratumoral
nanoparticle
genitourinary oncology
cancer
bladder
renal
prostate
Online Access:https://www.mdpi.com/2072-6694/11/4/577

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https://www.mdpi.com/2072-6694/11/4/577

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