4-Week repeated dose rat GLP toxicity study of oncolytic ECHO-7 virus Rigvir administered intramuscularly with a 4-week recovery period

4-Week repeated dose rat GLP toxicity study of oncolytic ECHO-7 virus Rigvir administered intramuscularly with a 4-week recovery period

The oncolytic ECHO-7 virus Rigvir was registered in Latvia in 2004 and later in Georgia, Armenia and Uzbekistan. No severe adverse events have been observed. During drug development good laboratory practice (GLP) pre-clinical toxicology studies are generally required by regulatory agencies. Since su...

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Bibliographic Details
Main Authors: Katarzyna Piwoni, Gilta Jaeckel, Agnija Rasa, Pēteris Alberts
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
ECHO-7 virus
Oncolytic virus
Rigvir
Virotherapy
Preclinical toxicology
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021000093

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http://www.sciencedirect.com/science/article/pii/S2214750021000093

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