Correlation among baseline variables yields non-uniformity of p-values.

A recent paper in Neurology used statistical techniques to investigate the integrity of the randomization in 33 clinical trials conducted by a group of investigators. Without justification, the approach assumed that there would be no impact of correlation among baseline variables. We investigated th...

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Bibliographic Details
Main Authors: Rebecca A Betensky, Sy Han Chiou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5590981?pdf=render