Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles

Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles

The epidermal growth factor receptor (EGFR) is an abundant membrane protein, which is essential for regulating many cellular processes including cell proliferation. In our earlier studies, we observed an activation of the EGFR and subsequent signaling events after the exposure of epithelial cells to...

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Bibliographic Details
Main Authors: Daniel Stöckmann, Tim Spannbrucker, Niloofar Ale-Agha, Philipp Jakobs, Christine Goy, Nadine Dyballa-Rukes, Tamara Hornstein, Alexander Kümper, Annette Kraegeloh, Judith Haendeler, Klaus Unfried
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Nanomaterials
Subjects:
tyrosine kinase receptor
caveolin-1
airway epithelium
lung inflammation
protein kinase B
Online Access:http://www.mdpi.com/2079-4991/8/4/267

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