Novel Immune Subsets and Related Cytokines: Emerging Players in the Progression of Liver Fibrosis

Novel Immune Subsets and Related Cytokines: Emerging Players in the Progression of Liver Fibrosis

Liver fibrosis is a pathological process caused by persistent chronic injury of the liver. Kupffer cells, natural killer (NK) cells, NKT cells, and dendritic cells (DCs), which are in close contact with T and B cells, serve to bridge innate and adaptive immunity in the liver. Meanwhile, an imbalance...

Full description

Bibliographic Details
Main Authors:	Minjie Wan, Jiawen Han, Lili Ding, Feng Hu, Pujun Gao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-04-01
Series:	Frontiers in Medicine
Subjects:	liver fibrosis T helper cells mucosa-associated invariant T cells innate lymphoid cells regulatory T cells hepatic stellate cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2021.604894/full

Similar Items

Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis
by: Su Yeon An, et al.
Published: (2021-03-01)

Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV-related liver fibrosis
by: Xiaoyan Li, et al.
Published: (2017-04-01)

Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis
by: Oliver Krenkel, et al.
Published: (2019-05-01)

Matrix Metalloproteinase’s Role in Producing and Curing of Liver Fibrosis
by: Hossein Baharvand, et al.
Published: (2009-01-01)

New Players in Immunity to Tuberculosis: The Host Microbiome, Lung Epithelium, and Innate Immune Cells
by: Nancy Gupta, et al.
Published: (2018-04-01)

A Review of Liver Fibrosis and Emerging Therapies
by: Rooshi Nathwani, et al.
Published: (2019-12-01)

Alterations of CD4+T Cell Subsets in Blood and Peritoneal Fluid in Different Stages of Endometriosis
by: Fatemeh Pashizeh, et al.
Published: (2020-10-01)

Adipose-derived mesenchymal stem cells inhibit activation of hepatic stellate cells in vitro and ameliorate rat liver fibrosis in vivo
by: Fuxiang Yu, et al.
Published: (2015-02-01)

Extracellular Vesicles From Hepatocytes Are Therapeutic for Toxin-Mediated Fibrosis and Gene Expression in the Liver
by: Xinlei Li, et al.
Published: (2020-01-01)

Plasticity of human CD4 T cell subsets
by: Jens eGeginat, et al.
Published: (2014-12-01)

Maintenance of immune homeostasis through ILC/T cell interactions
by: Nicole evon Burg, et al.
Published: (2015-08-01)

Commentary: Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation
by: Boning Zeng, et al.
Published: (2018-07-01)

Potential Role of Thymosin Beta 4 in Liver Fibrosis
by: Jieun Kim, et al.
Published: (2015-05-01)

The role of innate lymphoid cells and T helper cell activation in type 2 diabetic patients: a protocol for a systematic review and meta-analysis
by: Vuyolwethu Mxinwa, et al.
Published: (2019-09-01)

Dandelion prevents liver fibrosis, inflammatory response, and oxidative stress in rats
by: Alaaeldin Ahmed Hamza, et al.
Published: (2020-07-01)

RNA Sequencing and Bioinformatics Analysis Implicate the Regulatory Role of a Long Noncoding RNA-mRNA Network in Hepatic Stellate Cell Activation
by: Can-Jie Guo, et al.
Published: (2017-08-01)

Thrombin and factor Xa link the coagulation system with liver fibrosis
by: Ameet Dhar, et al.
Published: (2018-05-01)

Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway
by: Zhaoyan Kong, et al.
Published: (2019-01-01)

Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosis
by: Pengguo Chen, et al.
Published: (2015-12-01)

Geranylgeranylacetone attenuates fibrogenic activity and induces apoptosis in cultured human hepatic stellate cells and reduces liver fibrosis in carbon tetrachloride-treated mice
by: Takemasa Senoo, et al.
Published: (2018-02-01)

Demethyleneberberine Protects against Hepatic Fibrosis in Mice by Modulating NF-κB Signaling
by: Yongchen Wang, et al.
Published: (2016-06-01)

Placental Growth Factor Contributes to Liver Inflammation, Angiogenesis, Fibrosis in Mice by Promoting Hepatic Macrophage Recruitment and Activation
by: Xi Li, et al.
Published: (2017-07-01)

Epigenetic Mechanisms in Hepatic Stellate Cell Activation During Liver Fibrosis and Carcinogenesis
by: Marina Barcena-Varela, et al.
Published: (2019-05-01)

Seventeen-Year Journey Working With a Master
by: Jinfang Zhu
Published: (2018-05-01)

Molecular Pathways Modulated by Mesenchymal Stromal Cells and Their Extracellular Vesicles in Experimental Models of Liver Fibrosis
by: Giulia Chiabotto, et al.
Published: (2020-12-01)

Macrophage and innate lymphoid cell interplay in the genesis of fibrosis
by: Emily eHams, et al.
Published: (2015-11-01)

Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis
by: Simon Hohenester, et al.
Published: (2020-01-01)

CD4 T cells mediate both positive and negative regulation of the immune response to HIV infection: complex role of T follicular helper cells and Regulatory T cells in pathogenesis
by: Chansavath ePhetsouphanh, et al.
Published: (2015-01-01)

Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells
by: Jingmei Liu, et al.
Published: (2017-01-01)

Functional perturbation of classical natural killer and innate lymphoid cells in the oral mucosa during SIV infection
by: Haiying eLi, et al.
Published: (2013-01-01)

Hepatic Stellate Cells and microRNAs in Pathogenesis of Liver Fibrosis
by: Mio Kitano, et al.
Published: (2016-03-01)

The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis
by: Qianglin Chen, et al.
Published: (2019-12-01)

Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect
by: Xi Zhou, et al.
Published: (2021-06-01)

Carvedilol attenuates carbon tetrachloride-induced liver fibrosis and hepatic sinusoidal capillarization in mice
by: Wu Y, et al.
Published: (2019-08-01)

Nitric oxide augments mesenchymal stem cell ability to repair liver fibrosis
by: Ali Gibran, et al.
Published: (2012-04-01)

Pathophysiology and Treatment Options for Hepatic Fibrosis: Can It Be Completely Cured?
by: Arshi Khanam, et al.
Published: (2021-05-01)

Glycyrrizinic acid: pathophysiological aspects of fibrosis formation and effectiveness in treatment of liver diseases
by: Yu.М. Stepanov, et al.
Published: (2018-09-01)

Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice
by: Yosuke Osawa, et al.
Published: (2015-11-01)

Liver fibrosis and inflammation. A review
by: David Kershenobich Stalnikowitz, MD, PhD, et al.
Published: (2003-10-01)

Distribution of hepatic stellate cells and their role in the development of parasitic fibrosis and liver cirrhosis in domestic animals
by: Kukolj Vladimir, et al.
Published: (2015-01-01)

Cannot write session to /tmp/vufind_sessions/sess_8bd8gbvao128bp9o6unco3ssec