Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host

Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH seconda...

Full description

Bibliographic Details
Main Authors: Amey Dilip Sonavane, Pratibha Balasaheb Sonawane, Sachet Vijay Chandak, Pravin M Rathi
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/7337/15839_CE[Ra1]_F(AK)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf
id doaj-207f926de3944d3b8ce54251726b740b
record_format Article
spelling doaj-207f926de3944d3b8ce54251726b740b2020-11-25T02:54:03ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-03-01103OD03OD0510.7860/JCDR/2016/15839.7337Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent HostAmey Dilip Sonavane0Pratibha Balasaheb Sonawane1Sachet Vijay Chandak2Pravin M Rathi3Gastroenterology Fellow, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.Gastroenterology Fellow, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.Gastroenterology Fellow, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.Consultant Gastroenterologist, Department of Gastroenterology, Bombay Hospital and Institute of Medical Sciences, Mumbai, India.Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient.https://jcdr.net/articles/PDF/7337/15839_CE[Ra1]_F(AK)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdfclinical infectious diseasehaemophagocytosisinvasive fungal infections
collection DOAJ
language English
format Article
sources DOAJ
author Amey Dilip Sonavane
Pratibha Balasaheb Sonawane
Sachet Vijay Chandak
Pravin M Rathi
spellingShingle Amey Dilip Sonavane
Pratibha Balasaheb Sonawane
Sachet Vijay Chandak
Pravin M Rathi
Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
Journal of Clinical and Diagnostic Research
clinical infectious disease
haemophagocytosis
invasive fungal infections
author_facet Amey Dilip Sonavane
Pratibha Balasaheb Sonawane
Sachet Vijay Chandak
Pravin M Rathi
author_sort Amey Dilip Sonavane
title Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
title_short Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
title_full Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
title_fullStr Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
title_full_unstemmed Disseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
title_sort disseminated histoplasmosis with haemophagocytic lymphohistiocytosis in an immunocompetent host
publisher JCDR Research and Publications Private Limited
series Journal of Clinical and Diagnostic Research
issn 2249-782X
0973-709X
publishDate 2016-03-01
description Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient.
topic clinical infectious disease
haemophagocytosis
invasive fungal infections
url https://jcdr.net/articles/PDF/7337/15839_CE[Ra1]_F(AK)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf
work_keys_str_mv AT ameydilipsonavane disseminatedhistoplasmosiswithhaemophagocyticlymphohistiocytosisinanimmunocompetenthost
AT pratibhabalasahebsonawane disseminatedhistoplasmosiswithhaemophagocyticlymphohistiocytosisinanimmunocompetenthost
AT sachetvijaychandak disseminatedhistoplasmosiswithhaemophagocyticlymphohistiocytosisinanimmunocompetenthost
AT pravinmrathi disseminatedhistoplasmosiswithhaemophagocyticlymphohistiocytosisinanimmunocompetenthost
_version_ 1724722803491471360