PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics

PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics

Abstract Background Advanced stage laryngeal squamous cell carcinoma (LSCC) presents a poor prognosis; thus, there is a great need to identify novel prognostic molecular markers. Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) is thought to be a novel prognostic factor in several cancers,...

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Bibliographic Details
Main Authors: Xiaoli Sheng, Yunxian Li, Yixuan Li, Wenlin Liu, Zhongming Lu, Jiandong Zhan, Mimi Xu, Liangsi Chen, Xiaoning Luo, Gang Cai, Siyi Zhang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Laryngeal squamous cell carcinoma
PLOD2
Drug resistance
Cancer stem cells
Wnt/β-catenin pathway
Online Access:http://link.springer.com/article/10.1186/s12885-019-6029-y

Internet

http://link.springer.com/article/10.1186/s12885-019-6029-y

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