CD47 is highly expressed in gliomas and targeting CD47 is a promising therapeutic strategy
Gliomas are very malignant brain tumors that are difficult to treat. CD47 is an antiphagocytic molecule that binds to SIPRα on phagocytes. It is overexpressed on the plasma membranes of multiple human tumor cell types and is an important diagnostic and prognostic biomarker in many types of cancer. H...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-03-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/20587392211000899 |