Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation

Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation

A substantial number of human and mouse group 3 innate lymphoid cells (ILC3s) reside in secondary lymphoid organs, yet the phenotype and function of these ILC3s is incompletely understood. Here, we employed an unbiased cross-tissue transcriptomic approach to compare human ILC3s from non-inflamed lym...

Full description

Bibliographic Details
Main Authors: Yotam E. Bar-Ephraim, Ferry Cornelissen, Natalie Papazian, Tanja Konijn, Remco M. Hoogenboezem, Mathijs A. Sanders, Bart A. Westerman, Mehmet Gönültas, Jaap Kwekkeboom, Joke M.M. Den Haan, Rogier M. Reijmers, Reina E. Mebius, Tom Cupedo
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Subjects:
innate lymphoid cells
human
lymph node
spleen
tonsil
blood
NKp44
cytokines
ILC3
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471731375X

Internet

http://www.sciencedirect.com/science/article/pii/S221112471731375X

Similar Items