3,5-Diethoxy-3′-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury

3,5-Diethoxy-3′-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury

Hepatic stellate cells (HSCs) are involved in the pathogenesis of liver fibrosis. Resveratrol, 3,5,4′-trihydroxystilbene, is a dietary polyphenol found in natural food products. Here, we evaluated the anti-proliferative effects of a synthetic resveratrol derivative, 3,5-diethoxy-3&#824...

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Bibliographic Details
Main Authors: Phil Jun Lee, Hye-Jin Park, Namki Cho, Hong Pyo Kim
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
hepatic stellate cell (HSC)
3,5-diethoxy-3′-hydroxyresveratrol (DEHR)
caveolin-1 (CAV1)
heme oxygenase 1 (HO-1)
Online Access:https://www.mdpi.com/1420-3049/23/11/2833

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