Mal3 is a multi-copy suppressor of the sensitivity to microtubule-depolymerizing drugs and chromosome mis-segregation in a fission yeast pka1 mutant.
The cAMP-dependent protein kinase Pka1 is known as a regulator of glycogenesis, transition into meiosis, chronological aging, and stress responses in the fission yeast, Schizosaccharomyces pombe. We demonstrated here that Pka1 is responsible for normal growth in the presence of the microtubule-desta...
Main Authors: | Takuma Tanabe, Masayuki Yamaga, Makoto Kawamukai, Yasuhiro Matsuo |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0214803 |
Similar Items
-
Microtubule Depolymerization by Kinase Inhibitors: Unexpected Findings of Dual Inhibitors
by: Kenji Tanabe
Published: (2017-11-01) -
Centrosome age regulates kinetochore–microtubule stability and biases chromosome mis-segregation
by: Ivana Gasic, et al.
Published: (2015-08-01) -
Microtubule depolymerization potentiates alpha-synuclein oligomerization
by: Russell H Swerdlow, et al.
Published: (2010-01-01) -
Characterization of Microtubule Depolymerization by the HIV Protein Rev
by: Bedi, Shimpi
Published: (2009) -
Enhanced tumor cell killing by ultrasound after microtubule depolymerization
by: Aditi Singh, et al.
Published: (2021-09-01)