Lapatinib Induced Suicidal Death of Human Erythrocytes

Lapatinib Induced Suicidal Death of Human Erythrocytes

Background/Aims: The human epidermal growth factor receptors tyrosine kinase inhibitor lapatinib has been shown to trigger suicidal death or apoptosis of tumor cells and is thus used for the treatment of malignancy. Side effects of lapatinib include anemia, which could, at least in theory, result fr...

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Bibliographic Details
Main Authors: Jens Zierle, Rosi Bissinger, Jasmin Egler, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Lapatinib
Phosphatidylserine
Cell volume
Eryptosis
Calcium
Online Access:http://www.karger.com/Article/FullText/438583

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