STAT3: An Anti-Invasive Factor in Colorectal Cancer?

Signal Transducer and Activator of Transcription 3 (STAT3) is activated in a majority of cancers, and promotes tumorigenesis and even metastasis through transcriptional activation of its target genes. Recently, we discovered that STAT3 suppresses epithelial-to-mesenchymal transition (EMT) and thus...

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Bibliographic Details
Main Authors: Petrus Rudolf de Jong, Ji-Hun Mo, Alexandra R. Harris, Jongdae Lee, Eyal Raz
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/6/3/1394