Molecular Characterization of Trypanosoma evansi Mevalonate Kinase (TeMVK)

Molecular Characterization of Trypanosoma evansi Mevalonate Kinase (TeMVK)

The mevalonate pathway is an essential part of isoprenoid biosynthesis leading to production of a diverse class of >30,000 biomolecules including cholesterol, heme, and all steroid hormones. In trypanosomatids, the mevalonate pathway also generates dolichols, which play an essential role in c...

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Bibliographic Details
Main Authors: Daniel P. Duarte, Éden R. Ferreira, Fabio M. Lima, Franciane Batista, Michel De Groote, Eduardo Horjales, Luiz C. Miletti, Diana Bahia
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Trypanosoma evansi
mevalonate kinase
Surra
3-hydroxy-3-methylglutaryl-CoA reductase
enzyme activity
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00223/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00223/full

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