Inflammation in Dry Eye Syndrome: Identification and Targeting of Oxylipin-Mediated Mechanisms

Inflammation in Dry Eye Syndrome: Identification and Targeting of Oxylipin-Mediated Mechanisms

Dry eye syndrome (DES) is characterized by decreased tear production and stability, leading to desiccating stress, inflammation and corneal damage. DES treatment may involve targeting the contributing inflammatory pathways mediated by polyunsaturated fatty acids and their derivatives, oxylipins. Her...

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Bibliographic Details
Main Authors: Dmitry V. Chistyakov, Olga S. Gancharova, Viktoriia E. Baksheeva, Veronika V. Tiulina, Sergei V. Goriainov, Nadezhda V. Azbukina, Marina S. Tsarkova, Andrey A. Zamyatnin, Pavel P. Philippov, Marina G. Sergeeva, Ivan I. Senin, Evgeni Yu. Zernii
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
dry eye syndrome
inflammation
oxidative stress
corneal damage
tear lipidome
5-lipoxigenase
Online Access:https://www.mdpi.com/2227-9059/8/9/344

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