The Role of the Rho/ROCK Pathway in Ang II and TGF-β1-Induced Atrial Remodeling.

The Role of the Rho/ROCK Pathway in Ang II and TGF-β1-Induced Atrial Remodeling.

To study the role of the Rho/ROCK pathway in Ang II and TGF-β1-induced atrial remodeling.A canine atrial fibrillation (AF) model was established by rapid atrial pacing (RAP) of the left atrium. The roles of TGF-β1, the RhoA/ROCK signaling pathway and connective tissue growth factor (CTGF) in atrial...

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Bibliographic Details
Main Authors: Li-Juan Liu, Feng-Juan Yao, Gui-Hua Lu, Cheng-Gui Xu, Zhe Xu, Kai Tang, Yun-Jiu Cheng, Xiu-Ren Gao, Su-Hua Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017578?pdf=render

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