Maternal malnutrition and offspring sex determine juvenile obesity and metabolic disorders in a swine model of leptin resistance.

Maternal malnutrition and offspring sex determine juvenile obesity and metabolic disorders in a swine model of leptin resistance.

The present study aimed to determine, in a swine model of leptin resistance, the effects of type and timing of maternal malnutrition on growth patterns, adiposity and metabolic features of the progeny when exposed to an obesogenic diet during their juvenile development and possible concomitant effec...

Full description

Bibliographic Details
Main Authors:	Alicia Barbero, Susana Astiz, Clemente J Lopez-Bote, Maria L Perez-Solana, Miriam Ayuso, Isabel Garcia-Real, Antonio Gonzalez-Bulnes
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3813450?pdf=render

Similar Items

Fetal Sex Modulates Developmental Response to Maternal Malnutrition.
by: Antonio Gonzalez-Bulnes, et al.
Published: (2015-01-01)

Maternal undernutrition and offspring sex determine birth-weight, postnatal development and meat characteristics in traditional swine breeds
by: M. Vázquez-Gómez, et al.
Published: (2018-03-01)

Sex and breed-dependent organ development and metabolic responses in foetuses from lean and obese/leptin resistant swine.
by: Laura Torres-Rovira, et al.
Published: (2013-01-01)

Diet-Induced Swine Model with Obesity/Leptin Resistance for the Study of Metabolic Syndrome and Type 2 Diabetes
by: L. Torres-Rovira, et al.
Published: (2012-01-01)

The Role of Offspring Genotype-By-Sex Interactions, Independently of Environmental Cues, on the Phenotype Traits of an Obese Swine Model
by: Ana Heras-Molina, et al.
Published: (2020-12-01)

The Effects of Maternal Metformin Treatment on Late Prenatal and Early Postnatal Development of the Offspring Are Modulated by Sex
by: Consolacion Garcia-Contreras, et al.
Published: (2020-11-01)

Effects of L-Glutamine Supplementation during the Gestation of Gilts and Sows on the Offspring Development in a Traditional Swine Breed
by: Marta Vázquez-Gómez, et al.
Published: (2021-03-01)

A Cross-Sectional Study of Obesity Effects on the Metabolomic Profile of a Leptin-Resistant Swine Model
by: M. Victoria Sanz-Fernandez, et al.
Published: (2020-03-01)

Metformin Alleviates Obesity and Systemic Oxidative Stress in Obese Young Swine
by: Susana Astiz, et al.
Published: (2020-07-01)

Sex‐specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring
by: Elena I. Denisova, et al.
Published: (2020-01-01)

The effects of maternal employment on the sex role development of offspring
by: Hricik, Debra A.
Published: (2011)

Neonatal leptin treatment reverses the bone-suppressive effects of maternal undernutrition in adult rat offspring
by: Elwyn C. Firth, et al.
Published: (2017-08-01)

Leptin levels in rat offspring are modified by the ratio of linoleic to α-linolenic acid in the maternal diet
by: Marina Korotkova, et al.
Published: (2002-10-01)

Malnutrition during lactation as a metabolic imprinting factor inducing the feeding pattern of offspring rats when adults: The role of insulin and leptin
by: A.S. Moura, et al.
Published: (2002-05-01)

Does the Mother or Father Determine the Offspring Sex Ratio? Investigating the Relationship between Maternal Digit Ratio and Offspring Sex Ratio.
by: Tae Beom Kim, et al.
Published: (2015-01-01)

Serum Leptin Is a Biomarker of Malnutrition in Decompensated Cirrhosis.
by: Vikrant Rachakonda, et al.
Published: (2016-01-01)

Maternal Supplementation with Polyphenols and Omega-3 Fatty Acids during Pregnancy: Effects on Growth, Metabolism, and Body Composition of the Offspring
by: Ana Heras-Molina, et al.
Published: (2020-10-01)

Polyphenols and IUGR pregnancies: Maternal hydroxytyrosol supplementation improves prenatal and early-postnatal growth and metabolism of the offspring.
by: Marta Vazquez-Gomez, et al.
Published: (2017-01-01)

Polyphenols and IUGR Pregnancies: Effects of Maternal Hydroxytyrosol Supplementation on Postnatal Growth, Metabolism and Body Composition of the Offspring
by: Marta Vazquez-Gomez, et al.
Published: (2019-11-01)

Maternal protein malnutrition does not impair insulin secretion from pancreatic islets of offspring after transplantation into diabetic rats.
by: Renato Chaves Souto Branco, et al.
Published: (2012-01-01)

Maternal condition but not corticosterone is linked to offspring sex ratio in a passerine bird.
by: Lindsay J Henderson, et al.
Published: (2014-01-01)

Maternal prenatal stress exposure and sex-specific risk of severe infection in offspring.
by: Monique Robinson, et al.
Published: (2021-01-01)

The role of maternal preconception vitamin D status in human offspring sex ratio
by: Alexandra C. Purdue-Smithe, et al.
Published: (2021-05-01)

Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis
by: Atsuko Imai, et al.
Published: (2017-06-01)

Maternal Supplementation with Herbal Antioxidants during Pregnancy in Swine
by: Víctor H. Parraguez, et al.
Published: (2021-04-01)

Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice
by: Baoming Wang, et al.
Published: (2020-08-01)

Correction: Maternal Condition but Not Corticosterone Is Linked to Offspring Sex Ratio in a Passerine Bird
by: The Staff
Published: (2014-01-01)

Correction: Maternal Condition but Not Corticosterone Is Linked to Offspring Sex Ratio in a Passerine Bird.
Published: (2014-01-01)

Paternal malnutrition programs breast cancer risk and tumor metabolism in offspring
by: Raquel Santana da Cruz, et al.
Published: (2018-08-01)

Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring
by: Xian-Hua Lin, et al.
Published: (2021-01-01)

Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner
by: Simon Lecoutre, et al.
Published: (2017-08-01)

Maternal effects on offspring growth indicate post-weaning juvenile dependence in chimpanzees (Pan troglodytes verus)
by: Liran Samuni, et al.
Published: (2020-01-01)

Maternal Metabolic Demands Caused by Pregnancy and Lactation: Association with Productivity and Offspring Phenotype in High-Yielding Dairy Ewes
by: José Luis Pesántez-Pacheco, et al.
Published: (2019-05-01)

Offspring sex determines the impact of the maternal ACE I/D polymorphism on maternal glycaemic control during the last weeks of pregnancy
by: Berthold Hocher, et al.
Published: (2011-09-01)

The Effect of Neonatal Leptin Antagonism in Male Rat Offspring Is Dependent upon the Interaction between Prior Maternal Nutritional Status and Post-Weaning Diet
by: J. Beltrand, et al.
Published: (2012-01-01)

Maternal touch moderates sex differences in juvenile social play behavior.
by: Michelle N Edelmann, et al.
Published: (2013-01-01)

Maternal Nicotine Exposure Alters Hippocampal Microglia Polarization and Promotes Anti-inflammatory Signaling in Juvenile Offspring in Mice
by: Li Zhou, et al.
Published: (2021-05-01)

Altered vertebral and femoral bone structure in juvenile offspring of microswine subject to maternal low protein nutritional challenge
by: Stuart A. Lanham, et al.
Published: (2019-06-01)

Association of Nutritional Status and Serum Leptin in Offsprings of Diabetic Parents of Karachi, Pakistan
by: Meraj Rahim, et al.
Published: (2016-08-01)

Leptin and Ghrelin in Excessive Gestational Weight Gain—Association between Mothers and Offspring
by: Jolanta Patro-Małysza, et al.
Published: (2019-05-01)