"Effect of topical timolol on intraocular pressure in the presence of systemic indomethacin in normal subjects"

• Main Authors: Sud R, Malhotra Ajay
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 1988-01-01
• Series: Indian Journal of Ophthalmology
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=1988;volume=36;issue=2;spage=64;epage=66;aulast=Sud

In the present study on 60 normal subjects, the effect of 0.5% timolol eye drops on intraocular tension was assessed in the presence of oral indomethacin. The subjects were categorized in four groups for comparing the results. Also the side effects of timolol maleate were noted. The following conclusions were made:- 1. In cases in whom indomethacin was given along with timolol drops, average fall in intraocular tension was almost identical with those in whom timolol alone was used. 2. The ocular hypotensive effect of timolol maleate eve drops is not attenuated by indomethacin given orally; but before we can conclude that the simultaneous administration of timolol maleate eye drops and indomethacin is entirely without risk of attenuation. We must study the effect of combined administration in patients with glaucoma.