Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences

Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences

Early life trauma (ELT) may drive mood disorder phenomenology, nitro-oxidative pathways and impairments in semantic memory. There are no data regarding the impact of ELT on affective phenomenology and whether these pathways are mediated by staging or lowered lipid-associated antioxidant defences.

Bibliographic Details
Main Authors: Maes Michael, Congio Ana, Moraes Juliana Brum, Bonifacio Kamila Landucci, Barbosa Decio Sabbatini, Vargas Heber Odebrecht, Morris Gerwyn, Puri Basant K., Michelin Ana Paula, Nunes Sandra Odebrecht Vargas
Format: Article
Language:English
Published: De Gruyter 2018-11-01
Series:Biomolecular Concepts
Subjects:
depression
bipolar disorder
immune
inflammation
oxidative
nitrosative stress
Online Access:https://doi.org/10.1515/bmc-2018-0010
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spelling doaj-2025a3b8bce24ec9810bf98f2247ab952021-09-05T20:42:35ZengDe GruyterBiomolecular Concepts1868-50211868-503X2018-11-019111513010.1515/bmc-2018-0010bmc-2018-0010Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant DefencesMaes Michael0Congio Ana1Moraes Juliana Brum2Bonifacio Kamila Landucci3Barbosa Decio Sabbatini4Vargas Heber Odebrecht5Morris Gerwyn6Puri Basant K.7Michelin Ana Paula8Nunes Sandra Odebrecht Vargas9Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilIMPACT Strategic Research Centre, Deakin University, Geelong, Vic, AustraliaDepartment of Medicine, Imperial College London, London, UKHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, BrazilEarly life trauma (ELT) may drive mood disorder phenomenology, nitro-oxidative pathways and impairments in semantic memory. There are no data regarding the impact of ELT on affective phenomenology and whether these pathways are mediated by staging or lowered lipid-associated antioxidant defences.https://doi.org/10.1515/bmc-2018-0010depressionbipolar disorderimmuneinflammationoxidativenitrosative stress
collection DOAJ
language English
format Article
sources DOAJ
author Maes Michael
Congio Ana
Moraes Juliana Brum
Bonifacio Kamila Landucci
Barbosa Decio Sabbatini
Vargas Heber Odebrecht
Morris Gerwyn
Puri Basant K.
Michelin Ana Paula
Nunes Sandra Odebrecht Vargas
spellingShingle Maes Michael
Congio Ana
Moraes Juliana Brum
Bonifacio Kamila Landucci
Barbosa Decio Sabbatini
Vargas Heber Odebrecht
Morris Gerwyn
Puri Basant K.
Michelin Ana Paula
Nunes Sandra Odebrecht Vargas
Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences
Biomolecular Concepts
depression
bipolar disorder
immune
inflammation
oxidative
nitrosative stress
author_facet Maes Michael
Congio Ana
Moraes Juliana Brum
Bonifacio Kamila Landucci
Barbosa Decio Sabbatini
Vargas Heber Odebrecht
Morris Gerwyn
Puri Basant K.
Michelin Ana Paula
Nunes Sandra Odebrecht Vargas
author_sort Maes Michael
title Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences
title_short Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences
title_full Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences
title_fullStr Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences
title_full_unstemmed Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences
title_sort early life trauma predicts affective phenomenology and the effects are partly mediated by staging coupled with lowered lipid-associated antioxidant defences
publisher De Gruyter
series Biomolecular Concepts
issn 1868-5021
1868-503X
publishDate 2018-11-01
description Early life trauma (ELT) may drive mood disorder phenomenology, nitro-oxidative pathways and impairments in semantic memory. There are no data regarding the impact of ELT on affective phenomenology and whether these pathways are mediated by staging or lowered lipid-associated antioxidant defences.
topic depression
bipolar disorder
immune
inflammation
oxidative
nitrosative stress
url https://doi.org/10.1515/bmc-2018-0010
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