Endocytosis as a biological response in receptor pharmacology: evaluation by fluorescence microscopy.

The activation of G-protein coupled receptors by agonist compounds results in diverse biological responses in cells, such as the endocytosis process consisting in the translocation of receptors from the plasma membrane to the cytoplasm within internalizing vesicles or endosomes. In order to function...

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Bibliographic Details
Main Authors: Víctor M Campa, Almudena Capilla, María J Varela, Arlet M Acanda de la Rocha, Juan C Fernandez-Troyano, R Belén Barreiro, Juan F Lopez-Gimenez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388511?pdf=render