Stability Study of Isoniazid and Rifampicin Oral Solutions Using Hydroxypropyl-Β-Cyclodextrin to Treat Tuberculosis in Paediatrics

Stability Study of Isoniazid and Rifampicin Oral Solutions Using Hydroxypropyl-Β-Cyclodextrin to Treat Tuberculosis in Paediatrics

(1) Background: First-line antituberculosis treatment in paediatrics entails the administration of Isoniazid, Pyrazinamide, and Rifampicin. This study examines the possibility of developing a combined dose liquid formulation for oral use that would facilitate dose adjustment and adherence to treatme...

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Bibliographic Details
Main Authors: Ana Santoveña-Estévez, Javier Suárez-González, Amor R. Cáceres-Pérez, Zuleima Ruiz-Noda, Sara Machado-Rodríguez, Magdalena Echezarreta, Mabel Soriano, José B. Fariña
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
first-line antituberculosis paediatric treatment
dose combination
isoniazid
pyrazinamide
rifampicin
Online Access:https://www.mdpi.com/1999-4923/12/2/195

Internet

https://www.mdpi.com/1999-4923/12/2/195

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