The Emergence of Novel Sequence Type Strains Reveals an Evolutionary Process of Intraspecies Clone Shifting in ICU-Spreading Carbapenem-Resistant Klebsiella pneumoniae

The Emergence of Novel Sequence Type Strains Reveals an Evolutionary Process of Intraspecies Clone Shifting in ICU-Spreading Carbapenem-Resistant Klebsiella pneumoniae

Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an urgent public health problem worldwide, and its rapid evolution in the clinical environment has been a major concern. A total of 99 CRKP isolates spreading in the intensive care unit (ICU) setting were included and subjected to whole-genome seq...

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Bibliographic Details
Main Authors: Dongdong Zhao, Qiucheng Shi, Dandan Hu, Li Fang, Yihan Mao, Peng Lan, Xinhong Han, Ping Zhang, Huangdu Hu, Yanfei Wang, Jingjing Quan, Yunsong Yu, Yan Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
virulence
capsule biosynthesis locus
intraspecies shifting
recombination
carbapenem-resistant
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.691406/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.691406/full

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