Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes

Abstract Early changes in astrocyte energy metabolism are associated with late‐onset Alzheimer's disease (LOAD), but the underlying mechanism remains elusive. A previous study suggested an association between a synonymous SNP (rs1012672, C→T) in LRP6 gene and LOAD; and that is indeed correlated...

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Bibliographic Details
Main Authors: Hei‐Man Chow, Jacquelyne Ka‐Li Sun, Ronald P. Hart, Kenneth King‐Yip Cheng, Clara H. L. Hung, Tsun‐Ming Lau, Kin‐Ming Kwan
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202004993