Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 −/Δ7 mice

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 −/Δ7 mice

Abstract Background The use of Akkermansia muciniphila as potential therapeutic intervention is receiving increasing attention. Health benefits attributed to this bacterium include an improvement of metabolic disorders and exerting anti-inflammatory effects. The abundance of A. muciniphila is associ...

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Bibliographic Details
Main Authors: Benthe van der Lugt, Adriaan A. van Beek, Steven Aalvink, Ben Meijer, Bruno Sovran, Wilbert P. Vermeij, Renata M. C. Brandt, Willem M. de Vos, Huub F. J. Savelkoul, Wilma T. Steegenga, Clara Belzer
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Immunity & Ageing
Subjects:
Aging
Akkermansia muciniphila
Intestinal immunity
Mucus layer
Intestinal barrier
Online Access:http://link.springer.com/article/10.1186/s12979-019-0145-z

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