Antimicrobial susceptibility pattern of Acinetobacter species isolated from infected wounds at a tertiary care hospital

• Main Authors: Rosić Ivana, Rosić Nikola, Simović Slobodan
• Format: Article
• Language: English
• Published: Medicinsko društvo za racionalnu terapiju Republike Srbije 2013-01-01
• Series: Racionalna Terapija
• Subjects: Acinetobacter species; wound infection; resistance; choice of antibiotics
• Online Access: http://scindeks-clanci.ceon.rs/data/pdf/1821-0538/2013/1821-05381302015R.pdf

Bacteria of the genus Acinetobacter, especially species Acinetobacter baumanii, is one of the most important causes of infection in immunocompromised patients in hospital. The aim of this study was to determine susceptibility of Acinetobacter species isolated from swabs of inflamed wounds to antibiotics. The study was conducted in several departments of the Clinical Centre 'Kragujevac' through retrospective analysis of 220 Acinetobacter species isolates from surgical wounds in 2011. The isolates of Acinetobaster species were mostly sensitive to ampicillin-sulbactam, colistin and tigecycline in all hospital departments that were surveyed. Only minority of the isolated Acinetobacter species were susceptible to cotrimoxazole, amikacin, imipenem and/or meropenem. Antibiotics with the highest in vitro efficacy against Acinetobacter species were ampicillinsulbactam, colistin and tigecycline. Highly resistant Acinetobacter species were more frequently isolated from patients in Intensive Care Unit.