Building a better model of cancer

<p>Abstract</p> <p>The 2006 Cold Spring Harbor Laboratory meeting on the Mechanisms and Models of Cancer was held August 16–20. The meeting featured several hundred presentations of many short talks (mostly selected from the abstracts) and posters, with the airing of a number of ex...

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Bibliographic Details
Main Authors: DeGregori James, Marusyk Andriy
Format: Article
Language:English
Published: BMC 2006-10-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/1/1/24
Description
Summary:<p>Abstract</p> <p>The 2006 Cold Spring Harbor Laboratory meeting on the Mechanisms and Models of Cancer was held August 16–20. The meeting featured several hundred presentations of many short talks (mostly selected from the abstracts) and posters, with the airing of a number of exciting new discoveries. We will focus this meeting review on models of cancer (primarily mouse models), highlighting recent advances in new mouse models that better recapitulate sporadic tumorigenesis, demonstrations of tumor addiction to tumor suppressor inactivation, new insight into senescence as a tumor barrier, improved understanding of the evolutionary paths of cancer development, and environmental/immunological influences on cancer.</p>
ISSN:1747-1028